Unbeaten 49ers Face Stiff Test Against Seahawks Defense
The San Francisco 49ers travel to face the Seattle Seahawks on Sunday, October 11, 2026, with kickoff set for 4:25 p.m. ET at Lumen Field in Seattle. San Francisco arrives unbeaten at 4-0 after defeating Denver on October 4, while Seattle sits at 3-1 following a game against the Chargers that same day.
San Francisco's defense has been the foundation of its perfect start, allowing just 64 points through four games, an average of 16.0 per contest. The offense has contributed as well, ranking sixth in the NFL in rushing at 137.3 yards per game and eighth in passing at 251.8. Quarterback Brock Purdy has thrown at least two touchdown passes in every game this season, totaling 1,007 yards, 11 touchdowns and a single interception. Against Denver, he completed 19 of 30 passes for 218 yards and two scores. Running back Christian McCaffrey has found the end zone in three straight games, leading the team with 218 rushing yards and four touchdowns on 50 carries, including a 52-yard, one-score outing against the Broncos. volleyball orange cup
Seattle counters with a defense that has allowed 73 points through four games, an 18.25 average, and sits tied for fourth in the league in turnover margin at plus-3. The Seahawks' passing attack ranks 14th in the NFL at 237.0 yards per game, led by Jaxon Smith-Njigba, who has 481 receiving yards and six touchdowns on 32 catches, highlighted by a nine-catch, 155-yard, three-touchdown performance at Arizona on September 20. On the ground, Seattle ranks 13th at 110.3 yards per game, with Emanuel Wilson pacing the backfield at 190 yards on 53 carries, including 81 yards and a touchdown on 21 carries against the Chargers.
Oddsmakers at DraftKings list Seattle as 3-point favorites, with a total of 46.5 points. The Seahawks carry a moneyline of -161, while the 49ers are priced at +135. San Francisco's third-down conversion rate of 57.5 percent, best in the league, could prove decisive in controlling the clock and limiting Seattle's offensive possessions, while turnover margin figures to be a key factor given the Seahawks' takeaway production this season.
